Gynecology World Conference 2026

Abstract

Background: Menstrual pattern disturbances can significantly impact the reproductive health of females. However, the influence of chronic pancreatitis on menstrual patterns remains understudied. This study aimed to investigate the effect of chronic pancreatitis on menstrual patterns in reproductive females.

Methods: A cohort of reproductive females diagnosed with chronic pancreatitis or recovered from acute pancreatitis within the age range of 16-45 years was included in the study. A total of 154 women were enrolled over a period of 6 months at the Department of Obstetrics and Gynecology, in association with the Department of Gastroenterology at the All India Institute of Medical Sciences. Detailed history-taking, physical examinations, and hormonal assessments (LH, FSH, and AMH) were performed to evaluate menstrual patterns and assess potential confounding factors.

Results: Among the participants with chronic pancreatitis, menstrual pattern disturbances were observed. The active phase of chronic pancreatitis showed a higher prevalence of oligomenorrhea (9.6%) and heavy menstrual bleeding/polymenorrhea (1.9%) compared to the quiescent phase. However, these differences were not statistically significant (p = 0.170). Additionally, the study revealed variations in the duration of the menstrual cycle, with amenorrhea (20.2%) and oligomenorrhea (14.4%) reported by some participants. Dysmenorrhea was present in 9.6% of the participants. Reproductive outcomes among the participants with chronic pancreatitis varied, with the majority having at least one child, while a small proportion experienced infertility (1.9%) and pregnancy loss through abortion (17.3%).

Conclusion: This study provides evidence that chronic pancreatitis is associated with menstrual pattern disturbances in reproductive females. The findings suggest the need for increased attention to reproductive health in individuals with chronic pancreatitis. Further research with larger sample sizes and longitudinal designs is warranted to better understand the underlying mechanisms and long-term implications of these menstrual disturbances.