2nd Edition of Gynecology World Conference 2027

Speakers - gwc 2027

Mike Raven A. Cullantes, Speaker at Pediatric and Adolescent Gynecology Conference 2026

Mike Raven A. Cullantes

Mike Raven A. Cullantes

  • Designation: Southern Philippines Medical Center
  • Country: Philippines
  • Title: Pure Primary Giant Cell Tumor of the Uterus: A Case Report

Abstract

Giant cell tumor (GCT), also known as osteoclastoma, is a rare neoplasm characterized by the proliferation of osteoclast-type multinucleated giant cells. It is a generally benign but locally aggressive neoplasm characterized by a proliferation of mononuclear stromal cells and numerous osteoclast-like giant cells.

 Giant cell tumors (GCTs) of the uterus rarely encountered in gynecologic malignancies and may pose substantial diagnostic challenges. While traditionally regarded as a benign tumor, GCT of the uterus may demonstrate a benign or malignant  behavior and, in rare instances, pose significant diagnostic and therapeutic challenges.

This is a case of 50-year-old woman who presented with post menopausal bleeding managed initially as a malignant carcinosarcoma and underwent exploratory laparotomy with peritoneal cytology, extrafascial hysterectomy with bilateral salpingo-oophorectomy, infracolic omentectomy, and bilateral pelvic lymph node dissection and chemotherapy but on extensive pathologic review, belonged to the less than 0.1%  of a rare case of a benign pure giant cell tumor of the uterus.